SAMD8 Antikörper

Produktnummer ABIN265117

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SAMD8 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SAMD8 Antikörper (ABIN265117)

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAMD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SAMD8 Antikörper

Spezifität: This antibody reacts to Sphingomyelin synthase-related protein 1.

Aufreinigung: Purified

Immunogen: Full-length recombinant sphingomyelin synthase r fusion protein.

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 5-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu SAMD8

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Andere Bezeichnung: SAMD8 / SMSr

Hintergrund: Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.Synonyms: SAM domain-containing protein 8, Sphingomyelin synthase-related protein 1, Sterile alpha motif domain-containing protein 8

Gen-ID: 142891

NCBI Accession: NP_653261

UniProt: Q96LT4