GPR68 Antikörper

Produktnummer ABIN265065

Dieses Anti-GPR68-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GPR68 in WB, Func und IHC (fro). Geeignet für Human.

Kurzübersicht für GPR68 Antikörper (ABIN265065)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR68 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GPR68 Antikörper

Spezifität: This antibody recognizes OGR1.

Aufreinigung: Purified

Immunogen: Recombinant protein derived from human OGR1 (GPR68) protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL, Western blot should be visualized using a high sensitivitysecondary/substrate system (i. e. Pierce's SuperSignal West Femto Maximum SensitivitySubstrate).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.08 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Andere Bezeichnung: GPR68 / OGR1

Hintergrund: OGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing. SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.Synonyms: G-protein coupled receptor 68, GPR12A, Ovarian cancer G-protein coupled receptor 1, Sphingosylphosphorylcholine receptor

Gen-ID: 8111

NCBI Accession: NP_001171147

UniProt: Q15743