EPH Receptor B1 Antikörper

Produktnummer ABIN264959

Der Schaf Polyklonal anti-EPH Receptor B1 Antikörper wird verwendet zum Nachweis von EPH Receptor B1 in Proben von Human. Er wurde validiert für IP.

Kurzübersicht für EPH Receptor B1 Antikörper (ABIN264959)

Target: EPH Receptor B1 (EPHB1)

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-EPH Receptor B1 Antikörper

Spezifität: This antibody reacts to ephB1 (Elk receptor) - EXT.

Aufreinigung: Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 - 10 μg/mL. Immunoprecipitation: 10 - 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Andere Bezeichnung: EPHB1

Hintergrund: The immunogen used for the anti-human ephB1 (Elk receptor) -EXT region was a GST fusion protein ephB1 (Elk receptor) -EXT corresponding to amino acid sequence 16-351 of the N terminus region and having a molecular weight of 116 kD. ephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2

Gen-ID: 2047

NCBI Accession: NP_004432

UniProt: P54762

Pathways: RTK Signalweg