VAMP1 Antikörper

Produktnummer ABIN264917

Der Schaf Polyklonal Anti-VAMP1-Antikörper wurde für WB und IP validiert. Er ist geeignet, VAMP1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für VAMP1 Antikörper (ABIN264917)

Target: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Reaktivität: Human, Ratte

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser VAMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-VAMP1 Antikörper

Spezifität: This antibody reacts to VAMP 1/2.

Aufreinigung: Ammonium Sulfate Precipitation

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 - 10 μg/mL. Immunoprecipitation: 5 - 15 μg/mL. Positive Control: Rat synaptic vesicles.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.08 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu VAMP1

Target: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Andere Bezeichnung: VAMP-1 / Synaptobrevin-1

Hintergrund: Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.Synonyms: VAMP-1/2, Vesicle associated membrane protein 1 and 2

Gen-ID: 6843

NCBI Accession: NP_055046

UniProt: P23763