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Carboxy Methyl Lysine Antikörper (methylated)

CML EIA, WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN264528
  • Target Alle Carboxy Methyl Lysine (CML) Antikörper anzeigen
    Carboxy Methyl Lysine (CML)
    Bindungsspezifität
    methylated
    Wirt
    • 2
    Ziege
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Dieser Carboxy Methyl Lysine Antikörper ist unkonjugiert
    Applikation
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Aufreinigung
    CML-protein Sepharose affinity chromatography
    Immunogen
    Carboxymethylated Keyhole Limpet Hemocyanin (CML-KLH). Prepared by the reaction of the protein with glyoxylic acid.
    Top Product
    Discover our top product CML Primärantikörper
  • Applikationshinweise
    Western Blot. ELISA: 1: 4,000 - 1: 20,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL (OD280nm, E0.1% = 1.35)
    Buffer
    75 mM PBS, pH 7.2 containing 75 mM Sodium chloride and 0.5 mM EDTA and 0.02 % Sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Carboxy Methyl Lysine (CML)
    Andere Bezeichnung
    Carboxy Methyl Lysine (CML Produkte)
    Synonyme
    ALL antikoerper, BCR1 antikoerper, CML antikoerper, D22S11 antikoerper, D22S662 antikoerper, PHL antikoerper, BCR, RhoGEF and GTPase activating protein antikoerper, BCR antikoerper
    Substanzklasse
    Amino Acid
    Hintergrund
    Carboxymethyl Lysine is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.Synonyms: CML, Carboxymethyl-lysine
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