p130 Antikörper (N-Term)

Produktnummer ABIN264369

Der Maus Monoklonal anti-p130 Antikörper (Klon KAB40) (ABIN264369) detektiert spezifisch p130 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für p130 Antikörper (N-Term) (ABIN264369)

Target: p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser p130 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: KAB40

Produktdetails anti-p130 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.

Produktmerkmale: Synonyms: Retinoblastoma-like protein 2, RB2, 130 kDa retinoblastoma-associated protein, p130,Retinoblastoma-related protein 2, RBR-2, pRb2

Aufreinigung: Protein A/G chromatography.

Immunogen: GST fusion protein to the N terminus of p130.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Western Blots at 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch

Haltbarkeit: 12 months

Details zu p130

Target: p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

Andere Bezeichnung: RBL2 / p130

Hintergrund: P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 130 kDa retinoblastoma-associated protein, RB2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, p130, pRb2

Gen-ID: 5934

UniProt: Q08999

Pathways: Zellzyklus, Mitotic G1-G1/S Phases