p107 Antikörper (N-Term)

Produktnummer ABIN264368

Der Maus Monoklonal Anti-p107-Antikörper wurde für WB validiert. Er ist geeignet, p107 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für p107 Antikörper (N-Term) (ABIN264368)

Target: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser p107 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: KAB6

Produktdetails anti-p107 Antikörper

Bindungsspezifität: N-Term

Produktmerkmale: Synonyms: Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein, p107, pRb1

Aufreinigung: Protein A/G chromatography

Reinheit: > 95 % by SDS-PAGE

Immunogen: GST fusion protein to the N terminus of p107. Genename: RBL1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Western Blots at 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu p107

Target: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Andere Bezeichnung: RBL1

Hintergrund: P107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 107 kDa retinoblastoma-associated protein, Retinoblastoma-like protein 1, p107, pRb1

UniProt: P28749

Pathways: Zellzyklus, Mitotic G1-G1/S Phases