PAI1 Antikörper
Kurzübersicht für PAI1 Antikörper (ABIN264029)
Target
Alle PAI1 (SERPINE1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Synonyms: Serpin E1, PLANH1, Plasminogen Activator Inhibitor 1, PAI-1, PAI, Endothelial plasminogenactivator inhibitor
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Aufreinigung
- Protein A chromatography
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Reinheit
- > 98 % pure (SDS-PAGE)
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Immunogen
- Recombinant human PAI
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Isotyp
- IgG
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Applikationshinweise
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 2.5mg/mL (OD280nm, E0.1% = 1.36)
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Buffer
- 0.05 M Sodium phosphate, 0.5 M Sodium chloride, 1 mM EDTA, pH 6.6
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Lagerung
- -80 °C
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Informationen zur Lagerung
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Store the antibody at -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Andere Bezeichnung
- SERPINE1 / PAI1
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Hintergrund
- PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1
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UniProt
- P05121
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Pathways
- p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration
Target
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