ErbB2/Her2 Antikörper (Internal Region)

Produktnummer ABIN2613421

Dieser Anti-ErbB2/Her2 Antikörper ist ein Ziege Polyklonal Antikörper zur Detektion von ErbB2/Her2 in IHC und ELISA. Geeignet für Human.

Kurzübersicht für ErbB2/Her2 Antikörper (Internal Region) (ABIN2613421)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ErbB2/Her2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Güteklasse: Verified

Produktdetails anti-ErbB2/Her2 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: ERBB2 / HER2

Sequenz: PREYVNARHC LP

Spezifität: This antibody is expected to recognize both reported isoforms (NP_004439.2, NP_001005862.1). The immunizing peptide represents part of the extracellular domain.

Kreuzreaktivität: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: In paraffin embedded Human breast cancer shows cell membrane and cytoplasm staining in the affected cells of Her+ type and not in triple negative type. Recommended concentration, 4-6 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Andere Bezeichnung: ERBB2

Hintergrund: ERBB2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1, c-erb B2/neu protein, herstatin, metastatic lymph node gene 19 protein, neuroblas

Gen-ID: 2064

NCBI Accession: NP_004439, NP_001005862

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development