Der Hamster Monoklonal Anti-TCR beta-Antikörper wurde für FACS, IP, IHC, IF und Func validiert. Er ist geeignet, TCR beta in Proben von Maus zu detektieren.
Produktnummer ABIN2568471
Kurzübersicht für TCR beta Antikörper (ABIN2568471)
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target
TCR beta
(T Cell Receptor (TCR) beta (TCR beta))
Andere Bezeichnung
TCR beta
Hintergrund
The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR). The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.