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IZUMO1 Antikörper
IZUMO1
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2568277
Produktdetails anti-IZUMO1 Antikörper
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Target
Alle IZUMO1 Antikörper anzeigen
IZUMO1
(Izumo Sperm-Egg Fusion 1 (IZUMO1))
Reaktivität
Alle Reaktivitäten für IZUMO1 Antikörper
Human
Wirt
Alle Wirte für IZUMO1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IZUMO1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für IZUMO1 Antikörper
Dieser IZUMO1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IZUMO1 Antikörper
ELISA, Western Blotting (WB)
Spezifität
IZUMO1 antibody is human specific. At least four isoforms of IZUMO1 are known to exist, this antibody will detect the two longest isoforms.
Aufreinigung
IZUMO1 antibody is affinity chromatography purified via peptide column.
Immunogen
IZUMO1 antibody was raised against an 18 amino acid peptide near the center of human IZUMO1
Isotyp
IgG
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Discover our top product IZUMO1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IZUMO1 antibody can be used for detection of IZUMO1 by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
IZUMO1 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
IZUMO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu IZUMO1
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Target
IZUMO1
(Izumo Sperm-Egg Fusion 1 (IZUMO1))
Andere Bezeichnung
IZUMO1 (IZUMO1 Produkte )
Synonyme
IZUMO antikoerper, 1700058F15Rik antikoerper, Izumo antikoerper, izumo sperm-egg fusion 1 antikoerper, Ras interacting protein 1 antikoerper, IZUMO1 antikoerper, RASIP1 antikoerper, Izumo1 antikoerper
Hintergrund
IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by alternative splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an inability to penetrate the plasma membrane of the egg (4).
Molekulargewicht
Predicted: 35, 39, 42 kDa Observed: 52 kDa
Gen-ID
284359
NCBI Accession
NP_872381
UniProt
Q8IYV9
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