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IL-12/IL-23 p40 Antikörper

Reaktivität: Maus FACS, ELISA, IF, IP, Func, WB Wirt: Ratte Monoclonal C17-8 unconjugated
Produktnummer ABIN2568231
  • Target Alle IL-12/IL-23 p40 Produkte
    IL-12/IL-23 p40
    Reaktivität
    • 11
    • 9
    • 1
    Maus
    Wirt
    • 11
    • 9
    Ratte
    Klonalität
    • 20
    Monoklonal
    Konjugat
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Dieser IL-12/IL-23 p40 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func), Western Blotting (WB)
    Spezifität
    The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Klon
    C17-8
    Isotyp
    IgG2a kappa
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    IL-12/IL-23 p40
    Abstract
    IL-12/IL-23 p40 Produkte
    Hintergrund
    The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.
    Gen-ID
    16160
    UniProt
    P43432
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