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FAS Antikörper

FAS Reaktivität: Human FACS, Func Wirt: Maus Monoclonal EOS9-1 unconjugated

Produktnummer ABIN2568063

Datenblatt (PDF)

Target Alle FAS Antikörper anzeigen

FAS (TNF Receptor Superfamily, Member 6 (FAS))
Reaktivität
225

62

62

19

8

7

4

4

3

3

2

1

1

1
Human
Wirt
157

101

4

3

2

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
155

113

1
Monoklonal
Konjugat
120

28

26

13

12

7

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser FAS Antikörper ist unkonjugiert
Applikation
158

129

72

58

39

34

30

26

26

19

16

11

8

5

5

4

4

2

2

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Spezifität

The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

EOS9-1

Isotyp

IgM kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

FAS (TNF Receptor Superfamily, Member 6 (FAS))

Andere Bezeichnung

CD95 (FAS Produkte)

Hintergrund

The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.

Gen-ID

355

UniProt

P25445

Pathways

p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity