The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 Molecule.
Aufreinigung
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Lagerung
4 °C
Informationen zur Lagerung
The product should be stored undiluted at 4°C. Do not freeze.
Target
CD8B
(CD8b Molecule (CD8B))
Andere Bezeichnung
CD8b
Hintergrund
The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 Molecule. The alpha and beta chains of the CD8 Molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.