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CD86 Antikörper (FITC)

CD86 Reaktivität: Maus FACS Wirt: Ratte Monoclonal GL-1 (GL1) FITC
Produktnummer ABIN2567950
  • Target Alle CD86 Antikörper anzeigen
    CD86
    Reaktivität
    • 148
    • 117
    • 56
    • 19
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    Maus
    Wirt
    • 88
    • 78
    • 71
    Ratte
    Klonalität
    • 173
    • 60
    • 2
    Monoklonal
    Konjugat
    • 85
    • 25
    • 20
    • 17
    • 11
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD86 Antikörper ist konjugiert mit FITC
    Applikation
    • 167
    • 94
    • 52
    • 43
    • 39
    • 34
    • 32
    • 25
    • 18
    • 16
    • 14
    • 13
    • 13
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells.
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Klon
    GL-1 (GL1)
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD86 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    CD86
    Andere Bezeichnung
    CD86 (CD86 Produkte)
    Hintergrund
    The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells. The memory CD4+ T lymphocytes express CD86 (as mRNA and protein). CD86, and the B7-1 (CD 80) molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T. B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity. The GL-1 antibody blocks the mixed lymphocyte reaction (MLR) and inhibits the T-cells stimulation by antigen-presenting cells. Mixtures of anti-B7-1 antibody and GL-1 were reported to inhibit the interaction between CD125 and its ligand with the in vivo priming of cytotoxic T lymphocytes.
    Gen-ID
    12524
    UniProt
    P42082
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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