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CD80 Antikörper (FITC)

CD80 Reaktivität: Maus FACS Wirt: Hamster Monoclonal 16-10A1 FITC

Produktnummer ABIN2567927

Datenblatt (PDF)

Target Alle CD80 Antikörper anzeigen

CD80
Reaktivität
151

109

46

8

6

6

1

1

1
Maus
Wirt
92

81

21

21

19

2

1
Hamster
Klonalität
154

80

2
Monoklonal
Konjugat
97

19

19

16

12

5

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD80 Antikörper ist konjugiert mit FITC
Applikation
139

93

69

39

39

25

14

13

13

13

11

10

10

6

5

4

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR).

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

16-10A1

Isotyp

IgG

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD80

Andere Bezeichnung

CD80 (CD80 Produkte)

Hintergrund

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Gen-ID

12519

UniProt

Q00609

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints