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CD80 Antikörper

CD80 Reaktivität: Maus FACS, Func Wirt: Maus Monoclonal 2D10-4 unconjugated

Produktnummer ABIN2567920

Datenblatt (PDF)

Target Alle CD80 Antikörper anzeigen

CD80
Reaktivität
147

113

46

7

6

6

1

1

1
Maus
Wirt
91

79

22

21

21

2

1
Maus
Passende Sekundärantikörper
Klonalität
155

79

2
Monoklonal
Konjugat
93

20

20

17

13

5

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD80 Antikörper ist unkonjugiert
Applikation
140

92

68

39

38

25

14

13

13

13

11

10

9

6

5

4

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Spezifität

The 2D10.4 antibody reacts with human CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR).

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

2D10-4

Isotyp

IgG1 kappa

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anti-CD80 (CD80) (AA 38-246) antibody
CD80 Reaktivität: Maus WB, IP, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 FITC

anti-CD80 (CD80) (AA 251-321) antibody
CD80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 APC

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PE

anti-CD80 (CD80) antibody
CD80 Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 2A2 unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD80

Andere Bezeichnung

CD80 (CD80 Produkte)

Hintergrund

The 2D10.4 antibody reacts with human CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Gen-ID

941

UniProt

P33681

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints