ITGA2 Antikörper
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- Target Alle ITGA2 Antikörper anzeigen
- ITGA2 (Integrin alpha 2 (ITGA2))
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGA2 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Functional Studies (Func)
- Spezifität
- The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1).
- Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Klon
- HMa2
- Isotyp
- IgG
- Top Product
- Discover our top product ITGA2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Andere Bezeichnung
- CD49b (ITGA2 Produkte)
- Hintergrund
- The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1). VLA-2 is expressed on NK-T cells, epithelial cells, platelets, and CD+4 T lymphocytes. It is the receptor for laminin and collagen and is upregulated in response to mitogens. The Hma2 antibody is reported to partially block the interaction with collagen in T cells, but not NK cells.
- Gen-ID
- 16398
- UniProt
- Q62469
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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