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CD3 epsilon Antikörper (PE-Cy7)

CD3E Reaktivität: Maus FACS Wirt: Hamster Monoclonal 145-2C11 PE-Cy7

Produktnummer ABIN2567613

Datenblatt (PDF)

Target Alle CD3 epsilon (CD3E) Antikörper anzeigen

CD3 epsilon (CD3E)
Reaktivität
230

177

51

42

18

8

8

8

7

4

4

4

4

3

3

3

3

3

3

1

1

1

1

1
Maus
Wirt
133

128

49

23

23

10

1

1

1
Hamster
Klonalität
251

112

6
Monoklonal
Konjugat
142

32

29

23

18

8

8

6

5

5

5

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD3 epsilon Antikörper ist konjugiert mit PE-Cy7
Applikation
270

146

105

81

80

73

28

27

23

22

14

14

13

13

8

6

5

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

145-2C11

Isotyp

IgG

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CD3E Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

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anti-CD3 epsilon (CD3E) (AA 28-185) antibody
CD3E Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 23-207) antibody
CD3E Reaktivität: Human WB, IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD3 epsilon (CD3E)

Andere Bezeichnung

CD3e (CD3E Produkte)

Hintergrund

The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.

Gen-ID

12501

UniProt

P22646

Pathways

T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway