Leptin Receptor Antikörper (AA 901-1000) (PE)
Kurzübersicht für Leptin Receptor Antikörper (AA 901-1000) (PE) (ABIN2559727)
Target
Alle Leptin Receptor (LEPR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 901-1000
- 
                                            Spezifität
- This antibody will recognize the Isoform B variant only
- 
                                            Kreuzreaktivität
- Human, Maus, Schwein, Ratte
- 
                                            Homologie
- Dog,Cow,Sheep
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- FCM 1:20-100
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            Haltbarkeit
- 12 months
 
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- 
    - 
                                            : "Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis."    in: International immunology, Vol. 28, Issue 4, pp. 197-208, (2016)         (PubMed).        
 
 
- 
                                            : "Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis."    in: International immunology, Vol. 28, Issue 4, pp. 197-208, (2016)         (PubMed).        
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    - Leptin Receptor (LEPR)
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                                            Andere Bezeichnung
- Leptin receptor (Isoform B)
- 
                                            Hintergrund
- 
                        Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB, LEPR_MOUSE Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity). 
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                                            Gen-ID
- 3953
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                                            UniProt
- P48357
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                                            Pathways
- JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
 Target
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