Phosphoserine Antikörper (FITC)

Produktnummer ABIN2486261

Dieses Anti-Phosphoserine-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Phosphoserine in WB, ELISA, IP, IHC, ICC und IF. Geeignet für .

Kurzübersicht für Phosphoserine Antikörper (FITC) (ABIN2486261)

Target: Phosphoserine

Reaktivität: Bitte anfragen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phosphoserine Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-Phosphoserine Antikörper (FITC)

Spezifität: Detects proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine.

Aufreinigung: Peptide Affinity Purified

Immunogen: Phosphoserine conjugated to KLH, and phosvitin mixture

Anwendungsinformationen

Applikationshinweise:

• WB (1:500)
• ICC/IF (1:50)
• ELISA (1:250)
• IP (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

2 μg/ml of ABIN2486261 was sufficient for detection of phosphorylation signal in western blot analysis using human MMRU cells treated with 0.1 μM okadaic acid.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 50 % glycerol, 0.01 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu Phosphoserine

Target: Phosphoserine

Substanzklasse: Amino Acid

Hintergrund: Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine, others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).