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Phosphoserine Antikörper (Atto 390)

WB, ELISA, IP, IHC, ICC, IF Wirt: Kaninchen Polyclonal Atto 390
Produktnummer ABIN2486250
  • Target Alle Phosphoserine Produkte
    Phosphoserine
    Reaktivität
    Bitte anfragen
    Wirt
    • 29
    • 14
    Kaninchen
    Klonalität
    • 30
    • 13
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Phosphoserine Antikörper ist konjugiert mit Atto 390
    Applikation
    • 41
    • 20
    • 18
    • 10
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine.
    Aufreinigung
    Peptide Affinity Purified
    Immunogen
    Phosphoserine conjugated to KLH, and phosvitin mixture
  • Applikationshinweise
    • WB (1:500)
    • ICC/IF (1:50)
    • ELISA (1:250)
    • IP (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    2 μg/ml of ABIN2486250 was sufficient for detection of phosphorylation signal in western blot analysis using human MMRU cells treated with 0.1 μM okadaic acid.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.01 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    Phosphoserine
    Abstract
    Phosphoserine Produkte
    Substanzklasse
    Amino Acid
    Hintergrund
    Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine, others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).
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