ASIC1 Antikörper (AA 460-526) (APC)
Kurzübersicht für ASIC1 Antikörper (AA 460-526) (APC) (ABIN2483691)
Target
Alle ASIC1 (ACCN2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 460-526
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Spezifität
- Detects ~60 kDa.
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Protein G Purified
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Immunogen
- Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1
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Isotyp
- IgG1
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Applikationshinweise
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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1 μg/ml of ABIN2483691 was sufficient for detection of ASIC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
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Andere Bezeichnung
- ASIC1
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Hintergrund
- Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. Insitu hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety.
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Gen-ID
- 11419
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NCBI Accession
- NP_033727
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UniProt
- Q6NXK8
Target
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