CACNA1H Antikörper (AA 1019-1293) (APC)

Produktnummer ABIN2482858

Produktdetails anti-CACNA1H Antikörper (APC)

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Bindungsspezifität: AA 1019-1293

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CACNA1H Antikörper ist konjugiert mit APC

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Spezifität: Detects ~260 kDa. No cross-reactivity against Cav1.3.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2

Klon: N55-10 (Formerly S55-10)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2482858 was sufficient for detection of Cav3.2 in 10 μg of HEK cell lysate expressing Cav3.2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu CACNA1H

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Andere Bezeichnung: Cav3.2 (CACNA1H Produkte)

Hintergrund: CaV3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (1, 2). Studies also suggest that the up-regulations of CaV3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (3).

Gen-ID: 8912

NCBI Accession: NP_001005407

UniProt: O95180

Pathways: C21-Steroid Hormone Metabolic Process