PSMA Antikörper (C-Term)

Produktnummer ABIN2470727

Der Kaninchen Polyklonal Anti-PSMA-Antikörper wurde für IHC validiert. Er ist geeignet, PSMA in Proben von Human zu detektieren.

Kurzübersicht für PSMA Antikörper (C-Term) (ABIN2470727)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-PSMA Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Immunoaffinity Chromatography

Immunogen: FOLH1 antibody was raised against amino acids from the C-Terminus of FOLH1 (Human).

Anwendungsinformationen

Applikationshinweise: FOLH1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, BSA, sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store FOLH1 antibody at 4 °C or -20 °C.

Details zu PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Andere Bezeichnung: FOLH1

Hintergrund: PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

Gen-ID: 2346

UniProt: Q04609