Cullin 3 Antikörper (N-Term)
Kurzübersicht für Cullin 3 Antikörper (N-Term) (ABIN2470220)
Target
Alle Cullin 3 (CUL3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Aufreinigung
- Delipidation and Defibrination
-
Immunogen
- Cullin 3 antibody was raised against amino acids 1-12 from the N-Terminus of Cullin 3 (Human).
-
-
anti-Cullin 3 (CUL3) antibody
CUL3 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Cullin 3 (CUL3) antibodyCUL3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 3 (CUL3) (AA 411-510) antibodyCUL3 Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 3 (CUL3) (AA 569-768) antibodyCUL3 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 3 (CUL3) antibodyCUL3 Reaktivität: Human WB, FACS, ICC Wirt: Kaninchen Monoclonal 23GB1560 unconjugated Recombinant Antibody
anti-Cullin 3 (CUL3) (AA 650-700) antibodyCUL3 Reaktivität: Human, Maus WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 3 (CUL3) (AA 565-684) antibodyCUL3 Reaktivität: Human, Maus, Ratte, Huhn, Hund WB, IF Wirt: Maus Monoclonal 3-CUL unconjugated
anti-Cullin 3 (CUL3) (AA 301-400) antibodyCUL3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1A3 unconjugated
anti-Cullin 3 (CUL3) (AA 650-700) antibodyCUL3 Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 3 (CUL3) antibodyCUL3 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Monoclonal 7B6 unconjugated Recombinant Antibody
-
-
Applikationshinweise
- Cullin 3 antibody can be used in ELISA starting at 1:1000, and immunohistochemistry starting at 10 μg/mL.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- 0.01 % Sodium azide
-
Handhabung
- As with all antibodies avoid freeze/thaw cycles.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store Cullin 3 antibody at 4 °C or -20 °C.
-
-
- Cullin 3 (CUL3)
-
Andere Bezeichnung
- Cullin 3
-
Hintergrund
- Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 3 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul3 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul3 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Unlike Cul1 and Cul2, Cul3 seems not to be a part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Cul3 also interacts with RNF7 and is part of a complex with TIP120A/CAND1, Cyclin E and RBX1.
-
Gen-ID
- 8452
-
UniProt
- Q13618
-
Pathways
- M Phase
Target
-
