USP18 Antikörper (AA 40-49)

Produktnummer ABIN2469597

Produktdetails anti-USP18 Antikörper

Target: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Bindungsspezifität: AA 40-49

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Aufreinigung: Immunoaffinity Chromatography

Immunogen: USP18 antibody was raised against amino acids 40 - 49 of USP18 (Human).

Anwendungsinformationen

Applikationshinweise: USP18 antibody can be used in ELISA starting at 1:10000 - 1:50000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store USP18 antibody at 4 °C or -20 °C.

Details zu USP18

Target: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Andere Bezeichnung: USP18 (USP18 Produkte)

Hintergrund: UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.

Gen-ID: 11274

UniProt: Q9UMW8