IL-24 Antikörper (AA 100-150)
Kurzübersicht für IL-24 Antikörper (AA 100-150) (ABIN2469581)
Target
Alle IL-24 (IL24) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 100-150
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Aufreinigung
- Protein G Column
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Immunogen
- IL - 24 antibody was raised against a portion of amino acids 100 - 150 of IL - 24 (Human).
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Isotyp
- IgG
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Applikationshinweise
- IL-24 antibody can be used in ELISA starting at 1:2500 - 1:10000, Western Blot starting at 1:250 - 1:1000, immunohistochemistry starting at 5 μg/mL, immunocytochemistry, and immunofluorescence starting at 1:100 - 1:500.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, 0.2 % gelatin, 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- As with all antibodies avoid freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store IL-24 antibody at 4 °C or -20 °C.
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- IL-24 (IL24) (Interleukin 24 (IL24))
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Andere Bezeichnung
- IL-24
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Hintergrund
- Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
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Gen-ID
- 11009
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UniProt
- Q13007
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagie
Target
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