IL-24 Antikörper (AA 100-150)

Produktnummer ABIN2469581

Der Kaninchen Polyklonal Anti-IL-24-Antikörper wurde für WB, IHC und FACS validiert. Er ist geeignet, IL-24 in Proben von Human, Affe und Gorilla zu detektieren.

Kurzübersicht für IL-24 Antikörper (AA 100-150) (ABIN2469581)

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reaktivität: Human, Affe, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-IL-24 Antikörper

Bindungsspezifität: AA 100-150

Aufreinigung: Protein G Column

Immunogen: IL - 24 antibody was raised against a portion of amino acids 100 - 150 of IL - 24 (Human).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-24 antibody can be used in ELISA starting at 1:2500 - 1:10000, Western Blot starting at 1:250 - 1:1000, immunohistochemistry starting at 5 μg/mL, immunocytochemistry, and immunofluorescence starting at 1:100 - 1:500.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store IL-24 antibody at 4 °C or -20 °C.

Details zu IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Andere Bezeichnung: IL-24

Hintergrund: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Gen-ID: 11009

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagie