PDE8B Antikörper (Internal Region)

Produktnummer ABIN2469456

Der Kaninchen Polyklonal anti-PDE8B Antikörper (ABIN2469456) detektiert spezifisch PDE8B in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Affe, Gibbon und Gorilla.

Kurzübersicht für PDE8B Antikörper (Internal Region) (ABIN2469456)

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Reaktivität: Human, Affe, Gibbon, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-PDE8B Antikörper

Bindungsspezifität: Internal Region

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: PDE8B antibody was raised against a peptide located near the internal domain of PDE8B (Human).

Anwendungsinformationen

Applikationshinweise: PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: PDE8B antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu PDE8B

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Andere Bezeichnung: PDE8B

Hintergrund: Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.

Gen-ID: 8622

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process