PDE8B Antikörper (Internal Region)
Kurzübersicht für PDE8B Antikörper (Internal Region) (ABIN2469456)
Target
Alle PDE8B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- Internal Region
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                                            Spezifität
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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                                            Aufreinigung
- Immunoaffinity Chromatography
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                                            Immunogen
- PDE8B antibody was raised against a peptide located near the internal domain of PDE8B (Human).
 
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                                            Applikationshinweise
- PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Buffer
- PBS, 0.1 % sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- As with all antibodies avoid freeze/thaw cycles.
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                                            Lagerung
- 4 °C/-80 °C
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                                            Informationen zur Lagerung
- PDE8B antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
 
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    - PDE8B (phosphodiesterase 8B (PDE8B))
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                                            Andere Bezeichnung
- PDE8B
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                                            Hintergrund
- Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.
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                                            Gen-ID
- 8622
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                                            UniProt
- O95263
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                                            Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
 Target
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