Der Kaninchen Polyklonal anti-CCR8 Antikörper (ABIN2469366) detektiert spezifisch CCR8 in ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Gorilla.
CCR8 antibody can be used in immunohistochemistry starting at 4.8 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-80 °C
Informationen zur Lagerung
CR8 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target
CCR8
(Chemokine (C-C Motif) Receptor 8 (CCR8))
Andere Bezeichnung
CCR8
Hintergrund
CCR8, a Chemokine Receptor, binds the CC-chemokine I-309, which is secreted by umbilical vein endothelial cells. CCR8 also binds viral monocyte inflammatory protein-I (vMIP-I), which is induced by Kaposi sarcoma-related human herpesvirus-8. CCR8 induces endothelial chemotaxis and may function as an HIV-1 co-receptor on primary human cells, contributing to HIV-1-induced thymic pathogenesis (Lee et al., 2000).