SGK1 Antikörper (AA 211-431)
Kurzübersicht für SGK1 Antikörper (AA 211-431) (ABIN2468035)
Target
Alle SGK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 211-431
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Aufreinigung
- Immunoaffinity Purified
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Applikationshinweise
- Serine/threonine-protein kinase Sgk1 antibody can be used for the detection of Serine/threonine-protein kinase Sgk1 by Western Blot.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline. No preservatives added.
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Konservierungsmittel
- Without preservative
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Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- SGK antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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Andere Bezeichnung
- SGK
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Hintergrund
- FUNCTION: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, Kv1.3, or EAAT1.
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Molekulargewicht
- 49 kDa (calculated)
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Gen-ID
- 6446
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NCBI Accession
- NP_005618
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UniProt
- O00141
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Pathways
- MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway
Target
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