AFP antibody can be used for the detection of AFP by Western blot, may also work for IHC and ICC.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Konservierungsmittel
Without preservative
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
AFP antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Target
alpha Fetoprotein (AFP)
(alpha-Fetoprotein (AFP))
Andere Bezeichnung
AFP
Hintergrund
Alpha-1-fetoprotein. alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.