Huntingtin Antikörper (N-Term)
Kurzübersicht für Huntingtin Antikörper (N-Term) (ABIN2464133)
Target
Alle Huntingtin (HTT) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Aufreinigung
- Affinity Purified
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Immunogen
- A synthetic peptide corresponding to the N-terminus.
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Isotyp
- IgG
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Applikationshinweise
- ELISA, Western (immuno) blotting, Immunostaining (in testing)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Huntingtin (HTT)
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Andere Bezeichnung
- Huntington Protein
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Hintergrund
- Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington s disease protein is ~350 kDa in size and is localized in the brain.
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Gen-ID
- 3064
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UniProt
- P42858
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Pathways
- PI3K-Akt Signalweg, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
Target
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