TYRO3 Antikörper (truncated)

Produktnummer ABIN2464119

Der Maus Monoklonal anti-TYRO3 Antikörper (Klon 1C10E8-9A3F2) (ABIN2464119) detektiert spezifisch TYRO3 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TYRO3 Antikörper (truncated) (ABIN2464119)

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TYRO3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: 1C10E8-9A3F2

Produktdetails anti-TYRO3 Antikörper

Bindungsspezifität: truncated

Immunogen: Ni-NTA purified truncated recombinant TYRO3 expressed in E. Coli strain BL21 (DE3).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot:1:500 - 1:2,000
IF:1:50 - 1:200
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: TYRO3 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu TYRO3

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Andere Bezeichnung: TYRO3

Hintergrund: Tyrosine-protein kinase (TYRO3) belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

Gen-ID: 7301

UniProt: Q06418

Pathways: RTK Signalweg