TYK2 Antikörper (truncated)
Kurzübersicht für TYK2 Antikörper (truncated) (ABIN2464118)
Target
Alle TYK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- truncated
-
Immunogen
- Ni-NTA purified truncated recombinant Tyk2 expressed in E. Coli strain BL21 (DE3).
-
Isotyp
- IgG1
-
-
anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibody
TYK2 Reaktivität: Human WB, ELISA, IF, IP, IHC (p) Wirt: Maus Monoclonal 6G12 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibodyTYK2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 6H1 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (pTyr1054), (pTyr1055) antibodyTYK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1-1187) antibodyTYK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (C-Term) antibodyTYK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 286-372) antibodyTYK2 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) antibodyTYK2 Reaktivität: Human ELISA Wirt: Maus Monoclonal 8G8B3 unconjugated
anti-Tyrosine Kinase 2 (TYK2) antibodyTYK2 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1020-1069) antibodyTYK2 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1021-1070) antibodyTYK2 Reaktivität: Human, Maus, Ratte, Affe, Hund, Pferd, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
-
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Ascitic fluid containing 0.03 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Tyk2 monoclonal antibody can be stored at -20 °C, stable for one year.
-
-
- TYK2 (Tyrosine Kinase 2 (TYK2))
-
Andere Bezeichnung
- Tyk2
-
Hintergrund
- Tyk2 (tyrosine kinase 2),with 1187-amino acid protein (about 131 kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.
-
Gen-ID
- 7297
-
UniProt
- P29597
-
Pathways
- JAK-STAT Signalweg, Hepatitis C
Target
-
