TYK2 Antikörper (truncated)

Produktnummer ABIN2464118

Der Maus Monoklonal Anti-TYK2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TYK2 in Proben von Human zu detektieren.

Kurzübersicht für TYK2 Antikörper (truncated) (ABIN2464118)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TYK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 8G8E9-8G9H5

Produktdetails anti-TYK2 Antikörper

Bindungsspezifität: truncated

Immunogen: Ni-NTA purified truncated recombinant Tyk2 expressed in E. Coli strain BL21 (DE3).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot:1:500 - 1:2,000

ELISA:Propose dilution 1:10,000.

Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: Tyk2 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung: Tyk2

Hintergrund: Tyk2 (tyrosine kinase 2),with 1187-amino acid protein (about 131 kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.

Gen-ID: 7297

UniProt: P29597

Pathways: JAK-STAT Signalweg, Hepatitis C