CIB1 Antikörper (truncated)

Produktnummer ABIN2464036

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CIB1 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CIB1 Antikörper (truncated) (ABIN2464036)

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CIB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 5A1F5E12-5A1H7E12

Produktdetails anti-CIB1 Antikörper

Bindungsspezifität: truncated

Immunogen: Ni-NTA purified truncated recombinant CIB1 expressed in E. Coli strain BL21 (DE3).

Anwendungsinformationen

Applikationshinweise: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: CIB1 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu CIB1

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Andere Bezeichnung: CIB1

Hintergrund: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

Gen-ID: 10519

NCBI Accession: NP_001264693

UniProt: Q99828