CDC23 Antikörper
Kurzübersicht für CDC23 Antikörper (ABIN2462655)
Target
Alle CDC23 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Aufreinigung
- Antibody is purified by protein A chromatography method.
-
Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDC23.
-
-
-
-
Applikationshinweise
- CDC23 antibody can be used for detection of CDC23 by ELISA at 1:312500. CDC23 antibody can be used for detection of CDC23 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
Konzentration
- 1 mg/mL
-
Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDC23 antibody at -20 °C.
-
-
- CDC23 (Cell Division Cycle 23 (CDC23))
-
Andere Bezeichnung
- CDC23
-
Hintergrund
- CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
-
Molekulargewicht
- 66 kDa, 73 kDa
-
Gen-ID
- 8697
-
NCBI Accession
- NP_004652
-
UniProt
- Q9UJX2
-
Pathways
- Protein targeting to Nucleus
Target
-