UBE2I Antikörper
Kurzübersicht für UBE2I Antikörper (ABIN2462650)
Target
Alle UBE2I Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antibody is purified by protein A chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2I.
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Applikationshinweise
- UBE2I antibody can be used for detection of UBE2I by ELISA at 1:312500. UBE2I antibody can be used for detection of UBE2I by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store UBE2I antibody at -20 °C.
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- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
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Andere Bezeichnung
- UBE2I
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Hintergrund
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
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Molekulargewicht
- 17 kDa, 18 kDa, 18 kDa, 18 kDa
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Gen-ID
- 7329
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NCBI Accession
- NP_003336
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UniProt
- P63279
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
Target
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