PKLR Antikörper

Produktnummer ABIN2462457

Dieses Anti-PKLR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PKLR in WB, ELISA und IHC. Geeignet für Human, Maus, Ratte, Hund und C. elegans.

Kurzübersicht für PKLR Antikörper (ABIN2462457)

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Reaktivität: Human, Maus, Ratte, Hund, C. elegans

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PKLR Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PKLR.

Anwendungsinformationen

Applikationshinweise: PKLR antibody can be used for detection of PKLR by ELISA at 1:62500. PKLR antibody can be used for detection of PKLR by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PKLR antibody at -20 °C.

Details zu PKLR

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Andere Bezeichnung: PKLR

Hintergrund: PKLR is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molekulargewicht: 58 kDa, 62 kDa

Gen-ID: 5313

NCBI Accession: NP_870986

Pathways: Ribonucleoside Biosynthetic Process