Der Kaninchen Polyklonal anti-SLC12A1 Antikörper (ABIN2462394) detektiert spezifisch SLC12A1 in WB, IHC und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus und Hund.
SLC12A1 antibody can be used for detection of SLC12A1 by ELISA at 1:312500. SLC12A1 antibody can be used for detection of SLC12A1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLC12A1 antibody at -20 °C.
Target
SLC12A1
(Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
Andere Bezeichnung
SLC12A1
Hintergrund
The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene.