EIF2S1 Antikörper

Produktnummer ABIN2462161

Produktdetails anti-EIF2S1 Antikörper

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Reaktivität: Human, Ratte, Maus, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2S1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EIF2S1.

Anwendungsinformationen

Applikationshinweise: EIF2S1 antibody can be used for detection of EIF2S1 by ELISA at 1:2500. EIF2S1 antibody can be used for detection of EIF2S1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EIF2S1 antibody at -20 °C.

Details zu EIF2S1

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Andere Bezeichnung: EIF2S1 (EIF2S1 Produkte)

Synonyme: EIF-2 antikoerper, EIF-2A antikoerper, EIF-2alpha antikoerper, EIF2 antikoerper, EIF2A antikoerper, Eif2s1 antikoerper, eif2s1l antikoerper, fb36a08 antikoerper, wu:fb36a08 antikoerper, zgc:56510 antikoerper, 0910001O23Rik antikoerper, 2410026C18Rik antikoerper, 35kDa antikoerper, Eif2a antikoerper, eIF2alpha antikoerper, eif2a antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 subunit alpha antikoerper, eukaryotic translation initiation factor 2, subunit 1 alpha a antikoerper, eukaryotic translation initiation factor 2, subunit 1 alpha antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, Eukaryotic translation initiation factor 2 subunit 1 antikoerper, eukaryotic translation initiation factor 2 subunit alpha L homeolog antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2S1 antikoerper, eif2s1a antikoerper, Eif2s1 antikoerper, eif2s1 antikoerper, LOC693063 antikoerper, CNI00230 antikoerper, THAPSDRAFT_105 antikoerper, if2a antikoerper, eif2s1.L antikoerper, eIF-2alpha antikoerper

Hintergrund: The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987).

Molekulargewicht: 35 kDa

Gen-ID: 1965

NCBI Accession: NP_004085

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C