TSG101 Antikörper
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- Target Alle TSG101 Antikörper anzeigen
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Reaktivität
- Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TSG101 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TSG101.
- Top Product
- Discover our top product TSG101 Primärantikörper
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- Applikationshinweise
- TSG101 antibody can be used for detection of TSG101 by ELISA at 1:312500. TSG101 antibody can be used for detection of TSG101 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store TSG101 antibody at -20 °C.
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- Target
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- Andere Bezeichnung
- TSG101 (TSG101 Produkte)
- Synonyme
- CG9712 antikoerper, DmTSG101 antikoerper, Dmel\\CG9712 antikoerper, ESCRT-I antikoerper, Tsg101 antikoerper, burs antikoerper, dTSg101 antikoerper, dTsg101 antikoerper, dVps23 antikoerper, ept antikoerper, tsg101 antikoerper, vps23 antikoerper, TSG101 antikoerper, MGC76193 antikoerper, TSG10 antikoerper, VPS23 antikoerper, AI255943 antikoerper, CC2 antikoerper, Rw antikoerper, zgc:86926 antikoerper, tumor susceptibility 101 antikoerper, Tumor susceptibility gene 101 antikoerper, Tumor Susceptibility Gene homolog antikoerper, tumor susceptibility gene 101 antikoerper, tumor susceptibility 101a antikoerper, tumor susceptibility 101 L homeolog antikoerper, TSG101 antikoerper, tsg-101 antikoerper, tsg101 antikoerper, Tsg101 antikoerper, tsg101a antikoerper, tsg101.L antikoerper
- Hintergrund
- TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. TSG101 contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of TSG101 appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 gene occur in high frequency in breast cancer. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
- Molekulargewicht
- 44 kDa
- Gen-ID
- 7251
- NCBI Accession
- NP_006283
- UniProt
- Q99816
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