TIMELESS Antikörper

Produktnummer ABIN2461712

Produktdetails anti-TIMELESS Antikörper

Target: TIMELESS (Timeless Homolog (TIMELESS))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMELESS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIMELESS.

Anwendungsinformationen

Applikationshinweise: TIMELESS antibody can be used for detection of TIMELESS by ELISA at 1:312500. TIMELESS antibody can be used for detection of TIMELESS by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIMELESS antibody at -20 °C.

Details zu TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Andere Bezeichnung: TIMELESS (TIMELESS Produkte)

Synonyme: TIM antikoerper, TIM1 antikoerper, hTIM antikoerper, C77407 antikoerper, Debt69 antikoerper, tim antikoerper, CG3234 antikoerper, Dmel\\CG3234 antikoerper, Ritsu antikoerper, Tim antikoerper, dTIM antikoerper, dTim antikoerper, dtim antikoerper, mel_tim antikoerper, rit antikoerper, tim1 antikoerper, XTimeless1 antikoerper, timeless antikoerper, timelessb antikoerper, TIMELESS antikoerper, MXC20.14 antikoerper, MXC20_14 antikoerper, htim antikoerper, im:6903167 antikoerper, wu:fa95g04 antikoerper, wu:fd23d07 antikoerper, timeless circadian regulator antikoerper, timeless circadian clock 1 antikoerper, timeless antikoerper, timeless circadian clock antikoerper, timeless circadian clock S homeolog antikoerper, timeless family protein antikoerper, TIMELESS antikoerper, Timeless antikoerper, tim antikoerper, timeless.S antikoerper, Tim antikoerper, ATIM antikoerper, timeless antikoerper, LOC100328917 antikoerper

Hintergrund: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.

Molekulargewicht: 139 kDa

Gen-ID: 8914

NCBI Accession: NP_003911

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism