ATG4B Antikörper

Produktnummer ABIN2460952

Produktdetails anti-ATG4B Antikörper

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATG4B.

Anwendungsinformationen

Applikationshinweise: ATG4B antibody can be used for detection of ATG4B by ELISA at 1:12500. ATG4B antibody can be used for detection of ATG4B by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATG4B antibody at -20 °C.

Details zu ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Andere Bezeichnung: ATG4B (ATG4B Produkte)

Synonyme: apg4b antikoerper, APG4B antikoerper, AUTL1 antikoerper, 2510009N07Rik antikoerper, AW048066 antikoerper, Apg4b antikoerper, Atg4bl antikoerper, Autl1 antikoerper, Aut2b2 antikoerper, autophagy related 4B cysteine peptidase antikoerper, autophagy-related 4b antikoerper, Peptidase family C54 protein antikoerper, cysteine protease ATG4B antikoerper, ATG4 autophagy related 4 homolog B (S. cerevisiae) antikoerper, autophagy related 4B, cysteine peptidase antikoerper, autophagy related 4B, cysteine peptidase L homeolog antikoerper, ATG4B antikoerper, Atg4b antikoerper, AT3G59950 antikoerper, Tsp_08582 antikoerper, Tsp_11599 antikoerper, atg4b antikoerper, atg4b.L antikoerper

Hintergrund: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molekulargewicht: 44 kDa, 36 kDa, 55 kDa, 54 kDa

Gen-ID: 23192

NCBI Accession: NP_037457

UniProt: Q9Y4P1

Pathways: Autophagie