Claudin 11 Antikörper

Produktnummer ABIN2460771

Dieses Anti-Claudin 11-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Claudin 11 in WB, ELISA und IHC. Geeignet für Human und Hund.

Kurzübersicht für Claudin 11 Antikörper (ABIN2460771)

Target: Claudin 11 (CLDN11)

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Claudin 11 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN11.

Anwendungsinformationen

Applikationshinweise: CLDN11 antibody can be used for detection of CLDN11 by ELISA at 1:312500. CLDN11 antibody can be used for detection of CLDN11 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLDN11 antibody at -20 °C.

Details zu Claudin 11

Target: Claudin 11 (CLDN11)

Andere Bezeichnung: CLDN11

Hintergrund: CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Molekulargewicht: 22 kDa

Gen-ID: 5010

NCBI Accession: NP_005593

UniProt: O75508

Pathways: Hepatitis C