WNT8B Antikörper

Produktnummer ABIN2460735

Der Kaninchen Polyklonal anti-WNT8B Antikörper (ABIN2460735) detektiert spezifisch WNT8B in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Hund.

Kurzübersicht für WNT8B Antikörper (ABIN2460735)

Target: WNT8B (Wingless-Type MMTV Integration Site Family, Member 8B (WNT8B))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-WNT8B Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WNT8B.

Anwendungsinformationen

Applikationshinweise: WNT8B antibody can be used for detection of WNT8B by ELISA at 1:1562500. WNT8B antibody can be used for detection of WNT8B by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WNT8B antibody at -20 °C.

Details zu WNT8B

Target: WNT8B (Wingless-Type MMTV Integration Site Family, Member 8B (WNT8B))

Andere Bezeichnung: WNT8B

Hintergrund: The WNT family consists of sereval secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT8B is a protein which shows 95 % , 86 % and 71 % amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95 %, 86 % and 71 % amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

Molekulargewicht: 39 kDa

Gen-ID: 7479

NCBI Accession: NP_003384

UniProt: Q93098

Pathways: WNT Signalweg