MYST2 Antikörper

Produktnummer ABIN2460592

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MYST2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Hund.

Kurzübersicht für MYST2 Antikörper (ABIN2460592)

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MYST2 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MYST2.

Anwendungsinformationen

Applikationshinweise: MYST2 antibody can be used for detection of MYST2 by ELISA at 1:62500. MYST2 antibody can be used for detection of MYST2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MYST2 antibody at -20 °C.

Details zu MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Andere Bezeichnung: MYST2

Hintergrund: MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.

Molekulargewicht: 71 kDa

Gen-ID: 11143

NCBI Accession: NP_008998

UniProt: O95251