CREB3 Antikörper

Produktnummer ABIN2460566

Der Kaninchen Polyklonal Anti-CREB3-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CREB3 in Proben von Human und Hund zu detektieren.

Kurzübersicht für CREB3 Antikörper (ABIN2460566)

Target: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CREB3 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREB3.

Anwendungsinformationen

Applikationshinweise: CREB3 antibody can be used for detection of CREB3 by ELISA at 1:312500. CREB3 antibody can be used for detection of CREB3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CREB3 antibody at -20 °C.

Details zu CREB3

Target: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Andere Bezeichnung: CREB3

Hintergrund: CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.

Molekulargewicht: 41 kDa

Gen-ID: 10488

NCBI Accession: NP_006359

UniProt: Q5TCV1

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response